Breast Cancer


Overview

Breast cancer is cancer that originates from the breast tissue. It can affect women of all ages but most commonly affects those above 40. It is potentially fatal but achieving a survival rate is also possible. There are 5 stages of breast cancer (stage 0, 1, 2, 3 and 4). Treatment at stage 0 & 1 can result in survival rates of above 90%.

Symptoms

Symptoms and Signs of Breast Cancer

See your doctor if you notice any of these signs:
  • A persistent lump or thickening in the breast or axilla that may or may not be painful
  • A change in the size or shape of the breast, such as swollen and thickened skin
  • A change in the colour or appearance of the skin of the breast, such as redness, dimpling or puckering
  • Retracted nipple
  • A persistent rash or scaliness around the nipple
  • Bleeding or any unusual discharge from the nipple

  Breast Screening Method


Mammography

Mammograms (breast X-rays) are important tests in the diagnosis of breast cancer. A mammogram is a low-dose X-ray of the breast which can pick up small changes that cannot be felt. Each breast is placed between two special plates and pressure is applied to get the best possible picture. Some women find mammography uncomfortable or even painful. However, it only lasts a few minutes and is not harmful.

Ultrasound

This test is painless and takes just a few minutes. Ultrasound uses sound waves to build up a picture of the inside of the body. It is generally used for women under 35 whose breasts are too dense to give a clear picture with mammography. It is also used to see if a lump is solid or contains fluid (a cyst). Ultrasound is often used with mammography in specialist breast clinics. A special gel is spread onto the breasts and a small device like a microphone, which emits sound waves, is passed over the area. The echoes from the soundwaves are converted into a picture by a computer.

Breast Cancer Statistic
According to the Cancer Incident in Peninsula Malaysia, 2003 – 2006, published in the Nasional Cancer Society (NRC), breast cancer is the top cancer at 18% followed by bowel cancer 11.9% during this period.
乳腺癌是源于乳房组织 癌症。它可影响所有年女,但40以上的女最 它可致命的,但也有存活的可能 。乳腺癌可分为阶段0,1,2,3,4,共5段。在01接受治疗有90的存活率。
症状
症状和乳腺癌的症状
看医生,如果你发现任何些迹象:
在乳房或腋下,是否有痛的持久性肿块或增厚
乳房的大小或形状的改,如皮肤或增厚
在乳房的皮肤的色或外的改,如红肿,凹陷或起
皮疹或鳞在
出血或乳任何异常变化
乳房检查方法
乳房X光摄影
乳房X光检查(乳房X射线)在乳腺癌的诊断扮演者重要的检验。乳房X光检查是一种低量X射线却能检验到微小变化的乳房。乳房会被两个特殊的板夹住并施加压力,以获得最佳可能的效果。有些妇女发现乳房X光检查会感觉到不舒服,甚至痛。但是,它只能持续几分钟,而不是有害的。
乳房超声波扫描
乳腺癌统计
根据在马来半岛的癌症病例,20032006年,发表于国际癌症协会,目前期间,乳腺癌占最多的 18%,其次是肠胃癌11.9

Basic Treatment For Breast Cancer

Basically the treatment of breast cancer are divided into 2 categories :-


Local therapy
Systemic therapy
which treat the cancer on site without affecting the rest of the body

refer to drug which can be given by mouth or directly into bloodstream to reach cancer cell anywhere in the body

       Surgery and radiation
Chemotherapy, hormone therapy & targeted therapy

Additional treatment is given to patient who had no detectable cancer to prevent the cancer from coming back. This is known as adjuvant therapy. The goal of adjuvant therapy is to kill the hidden cancer after surgery as doctor believe that even in the early stage of cancer, some cancer can spread to other part and not being detectable by normal screening or mammogram and later part will form new cancer.

Some patients are given treatment such as chemotherapy or hormone therapy before the surgery. The goal of this treatment is to shrink the tumor in hope that less extension operation is done. This is call neoadjuvant therapy.

Type of treatment :-

(1)     Surgery

There is 2 type of surgery :-

(a)    breast conserving surgery – it only removed part of the affected breast. Radiotherapy is recommended after this surgery.
(b)   mastectomy – to remove the entire breast

(2)     Radiation

Radiation is a high energy ray that destroy cancer cell. It is recommended :-

(a)  to breast conserving surgery to lower the chances of the cancer
 coming back.
(b) patient after mastectomy with tumor larger than 5 cm
(c)  to cancer that spread to other part of the body such as bone and etc.

Radiation can be given in 2 ways :-

(a)    external -  radiation is focus from a machine outside the body on the
                     affected area. The procedure itself is painless and each
                     treatment lasted a few minutes only.
                 (b)  internal -   it is know as Brachytherapy. Radioactive seed or pellet is
                                              planted into the breast tissue next to the cancer.

(3)     Chemotherapy

Chemotherapy is a treatment with cancer killing drugs that is given intravenously; injected into veins or by mouth. The drugs then reaches the cancer via the bloodstream. It is usually a cycle treatment.

It can be given to patient before or after surgery.

The chemo drug program to kill cell that divide quickly which is the way cancer grow. There are other cell of the body like the hair follicle, lining of mouth, bone marrow and intestine also divide quickly. As such these cell will be also affected by the chemo drug which lead to side effect.

Possible side effect are :-
(a)    hair loss
(b)   mouth sore
(c)    lost of appetite or increase of appetite
(d)   vomiting
(e)    lost of blood cell count.

               The bone marrow is the blood forming cell. Affecting the bone marrow
               bring about the possibilities of :-
 (a)    fatigue – due to low red blood cell count
 (b)   easy bruising – due to low pallet count
 (c)    increase chance of infection – due to low white blood count.

(4)     Hormone therapy

A woman ovaries is the main source of estrogen hormone. Estrogen promote the growth of cancer s that are hormone receptor positive. As such it is given to block estrogen. It is usually taken as a pill.

The common side effect of these drug is fatigue, hot flashes, vaginal dryness or discharge and mood swing.

(5)     Biological therapy

It works by using the body immune system to destroy cancer cell.
These drugs target breast cancer cell that have high level of HER2 protein.

               

               











No comments:

Post a Comment